Nanoparticles in Protein Formulation: Challenges, Current Trends and Future Perspectives

There’s plenty of room at the bottom was the title of the lecture given by Richard Feynman to introduce the concept of Nanotechnology to the world [1]. Over the last five decades, significant progress has been made in the understanding of materials at the nano scale level. There have been many developments and improvements in formulation of drugs, however; the delivery of drugs in the required quantity at the desired target site still remains a challenge [2]. Nanoparticles are designed using methodologies that permit complete control over physicochemical attributes at the molecular scale while overcoming pharmacokinetic limitations associated with using conventional methods [2,3].